|
|
S-adenosyl-L-methionine + 6-Mercaptopurine <=> S-adenosyl-L-homocysteine + 6-methylthiopurine + H+
|
2.1.1.67
thiopurine S-methyltransferase
2.1.1.9
thiol S-methyltransferase
|
–
–
|
K
|
| |
BRENDA:
BR43910
KEGG:
R03701;
R08236
MetaCyc:
THIOPURINE-S-METHYLTRANSFERASE-RXN
|
|
|
|
6-Mercaptopurine + 2 H2O + 2 O2 <=> 6-Thiourate + 2 H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
K
|
| |
BRENDA:
BS394670
KEGG:
R08235
|
|
|
|
6-Mercaptopurine + 5-phospho-alpha-D-ribose_1-diphosphate <=> 6-thio-IMP + diphosphate
|
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
|
K
|
| |
BRENDA:
BS396088
KEGG:
R08237
|
|
|
|
6-Mercaptopurine + H2O + O2 <=> 8-hydroxy-6-mercaptopurine + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
|
| |
BRENDA:
BS359356
SABIO-RK:
11907
|
|
|
|
Azathioprine <=> 6-Mercaptopurine + 1-Methyl-4-nitroimidazole
|
not assigned
|
–
|
K
|
| |
KEGG:
R08234
|
|
|
|
6-Mercaptopurine + 5-phospho-alpha-D-ribose_1-diphosphate <=> 6-mercaptopurine_ribonucleotide + diphosphate
|
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
|
|
| |
BRENDA:
BS355048
|
|
|
|
6-mercaptopurine_ribonucleoside + H2O <=> 6-Mercaptopurine + D-ribose
|
3.2.2.1
purine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
|
|
| |
BRENDA:
BS214509
|
|
|
|
1-Deoxy-1-(6-thiopurinyl)-beta-D-glucopyranosiduronamide + H2O <=> 6-Mercaptopurine + 1-deoxy-D-glucopyranosiduronamide
|
3.2.1.31
beta-glucuronidase
|
–
|
|
| |
BRENDA:
BS13969
|
|
|
|
Ammonium_1-deoxy-1-(6-thiopurinyl)-beta-D-glucopyranosidurate + H2O <=> 6-Mercaptopurine + ammonium_1-deoxy-(6-thiopurinyl)-beta-D-glucopyranosiduronate
|
3.2.1.31
beta-glucuronidase
|
–
|
|
| |
BRENDA:
BS13968
|
|
|
|
1-Deoxy-1-(6-thiopurinyl)-beta-D-glucopyranoside + H2O <=> 6-Mercaptopurine + D-glucose
|
3.2.1.31
beta-glucuronidase
|
–
|
|
| |
BRENDA:
BS13970
|
|
|
|
thymidine + 6-Mercaptopurine <=> thymine + 9-(2-deoxy-beta-D-ribofuranosyl)-6-mercaptopurine
|
2.4.2.6
nucleoside deoxyribosyltransferase
|
–
|
|
| |
BRENDA:
BS354919
|
|
|
|
6-mercaptopurine_riboside + H2O <=> 6-Mercaptopurine + D-ribose
|
3.2.2.2
inosine nucleosidase
|
–
|
|
| |
BRENDA:
BS94808
|
|
|
|
S-(5''-adenosyl)-L-methionine-d3_disulfate_salt + 6-Mercaptopurine <=> S-adenosyl-L-homocysteine-d3_disulfate_salt + 6-methylthiopurine
|
2.1.1.67
thiopurine S-methyltransferase
|
–
|
|
| |
BRENDA:
BS456351
|
|
|
|
6-mercaptopurine_riboside + phosphate <=> alpha-D-ribose_1-phosphate + 6-Mercaptopurine
|
2.4.2.1
purine-nucleoside phosphorylase
|
–
|
|
| |
BRENDA:
BS323178
|
|
|
|
6-Mercaptopurine + ATP + H2O <=> 6-Mercaptopurine + ADP + phosphate
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
| |
BRENDA:
BS141520
|
|
|
|
2''-deoxyuridine + 6-Mercaptopurine <=> 6-mercaptopurine_2-deoxy-D-ribose_5-phosphate + Uracil
|
2.4.2.6
nucleoside deoxyribosyltransferase
|
–
|
|
| |
BRENDA:
BS422346
|
|
